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Richard M. Murray Thomas E. and Doris Everhart Professor of Control & Dynamical Systems and Bioengineering California Institute of Technology Papers Research Group Teaching Contact

Quick Links: CDS 112/Ae 103b Group Schedule Feedback Systems Biomolecular Feedback Systems

Research

My group's research is in the application of feedback and control to networked systems, with applications in biology and autonomy. Current projects include work on biomolecular feedback systems, novel architectures for control systems, and networked control systems (see my research overview for more details).

Preprint archive Caltech theses Google Scholar

Active projects:

• Center for Harnessing Microbiota from Military Environments (CHARMME) (ARO)
• Layered T&E for Safety-Critical Autonomous Systems (AFOSR)
• Rules of Composition in Synthetic Biology Across Scales of Complexity: Theory and Tools (AFOSR)
• Multi-Layer, Composable and Programmable Biomolecular Circuits for Microbial Consortia (Army Research Office)
• Engineering Reliable Genetic Circuits for Characterization and Remediation of Soil Ecologies (Army Research Office)
• Deciphering the Rules of Nucleus Architecture with Synthetic Cells and Organelles (NSF)
• Safety-Critical Cyber-Physical Systems: From Validation & Verification to Test & Evaluation (NSF)
• Formal Methods for V&V and T&E of Autonomous Systems (AFOSR)
• Developing Standardized Cell-Free Platforms for Rapid Prototyping of Synthetic Biology Circuits and Pathways (NSF)

[Archive]

Group

Apurva Badithela (CDS) Mengyi Cao+ (Carnegie) Josefine Graebener (AE) Inigo Incer (CMS) Zoila Jurado (ME) Manisha Kapasiawala (BE) Alex Johnson* (BE)

Matthieu Kratz* (BE) Elin Larsson* (BE) John Marken (BE) Ioannis Mandralis* (AE) Zach Martinez* (BE) Kellan Moorse (CNS)

Nikos Mynhier° (BE) Blade Olson* (BE) Ayush Pandey (CDS) Mark Prator# (EAS) Miki Yun# (EAS) Yan Zhang (BBE)

* co-advised students

+ visiting researchers

° rotation students

† undergraduates

# research staff

Former graduate students:

• Joe Meyerowitz - PhD in Biochemistry and Molecular Biophysics, December 2022
• Andrey Shur - PhD in Bioengineering, December 2021
• Rory Williams - PhD in Bioengineering, December 2021
• Samuel Clamons - PhD in Bioengineering, September 2021

Dionysios Barmpoutis (thesis) Robert Behnken (thesis) Julia Badger (Braman) (thesis) Ania Baetica (thesis) Francesco Bullo (thesis) Robert Bodenheimer* John Carson (thesis) Karena Cai (thesis) Andrea Censi (thesis) Richard Cheng* (thesis) Benson Christalin# Tim Chung* Lars Cremean (thesis) Nadine Dabby* Raff D'Andrea* Sumanth Dathathri (thesis) Samantha (Feakins) Daly# Emzo de los Santos (thesis) Domitilla Del Vecchio (thesis) Mary Dunlop (thesis) William Dunbar (thesis) Michael Epstein (thesis) Alex Fax (thesis) Ioannis Filippidis (thesis) Anthony Fragoso (thesis) Sawyer Fuller (thesis) Melvin Flores (thesis)

Elisa Franco (thesis) Jimmy Fung (thesis) Marcella Gomez (thesis) Martha Grover (Gallivan) (thesis) Shaobin Guo (thesis) Vijay Gupta (thesis) Sonja Glavaski* Shuo Han (thesis) Adam Hayes* Sean Humbert (thesis) Victoria Hsiao (thesis) Ali Jadbabaie* (thesis) Zhipu Jin (thesis) Vanessa Jonsson (thesis) Scott Kelly (thesis) Dmitriy Kogan# Javad Lavaei* (thesis) Andrew Lewis (thesis) Scott Livingston (thesis) Reed McCardell (thesis) Robert M'Closkey (thesis) Mark Milam (thesis) Michiel van Nieuwstadt (thesis) Ivan Papusha (thesis) James Parkin (thesis) Tung Phan (thesis) William Poole (thesis)

Muruhan Rathinam (thesis) Xinying (Cindy) Ren (thesis) Clancy Rowley* Ben Shapiro (thesis) Ling Shi (thesis) Vipul Singhal (thesis) Demetri Spanos (thesis) Zachary Sun (thesis)/ Sudipto Sur (thesis) Anandh Swaminathan (thesis) Anu Thubagere* (thesis) Amber Thweatt# Jorge Tierno* Abhishek Tiwari (thesis) Pete Trautman (thesis) Stephanie Tsuei# David van Gogh# Tony Vanelli# (thesis) Ophelia Venturelli (thesis) Yong Wang (thesis) Steve Waydo* (thesis) Eric Wolff (thesis) Nok Wongpiromsarn (thesis) Yong Wu (thesis) Huan (Mumu) Xu (thesis) Enoch Yeung (thesis) Simon Yeung (thesis)

# Masters or Engineers degree    * Co-advised student

Former postdocs:

• Chelsea Hu (2018-22) - BE Postdoctoral Fellow
• Ersin Das (2021-22) - CMS Postdoctoral Fellow
• Michaelle Mayalu (2017-22) - CMS Postdoctoral Fellow
• David Garcia (2020-21) - BE Postdoctoral Fellow
• Leopold Green (2018-21) - BE Postdoctoral Fellow

Raktim Bhattacharya (2002-04) Brianno Coller (1995-97) Noel du Toit (2011) Chuchu Fan (2019-20) Samira Farahani (2014-15) Jen Ge (2016-18) Sofie Haesaert (2016-18) Yutaka Hori (2013-16) Tamer Inanc (2002-04) Jongmin Kim (2010-14) Eric Klavins* (2001-03)

Feng-Li Lian (2001-02) Jun Liu (2011-2012) Catherine McGhan (2014-16) John McManus* (2018-19) Yilin Mo (2013-15) Kristi Morgansen (1999-2001) Pascal Morin (1996-97) Yasamin Mostofi (2004-06) Reza Olfati-Saber (2001-04) Yizhar Or (2007-09) Necmiye Ozay (2010-13)

Pavithra Prabhakar (2011-12) Nicolas Petit (2001-02) Vasu Raman (2013-15) Henrik Sandberg (2005-07) Shaunak Sen (2011-12) B. N. Shashikanth* (1998-2000) Dan Siegal (2012-15) Andrew Straw* (2010) Willem Sluis (1994-96) Herbert Streumper (1997-99) Ufuk Topcu (2008-12)

Additional group alumni:   SURF    Undergrads    Visitors

Teaching

The list below is the courses that I have taught at Caltech (or at least most of them). The course links will take you to the (current) course homepage, where you can find the syllabus, handouts, and homework sets. The links for specific terms take you to the course homepage for that term. Links to older courses are available on a separate page.

• ACM/EE 116 - Probability and Random Processes (Fa11)
• BE 107 - Exploring Biological Principles Through Bio-Inspired Design (Sp15, Sp16, Sp19)
• BE 150/Bi 250b - Systems Biology (Wi11, Wi12, Wi13, Sp14)
• CS/EE/ME 75 - Introduction to Multi-Disciplinary Systems Engineering (04-05, 06-07, 10-11, 15-16)
• CDS 90 - Senior Thesis in Control and Dynamical Systems (2004-2014, 2020-)
• CDS 101/110 - Analysis and Design of Feedback Systems (Fa97, Fa01, Fa02, Fa03, Fa04, Fa06, Fa07, Fa08, Fa12, Fa15)
• CDS 112 - Optimization-Based Control (Wi98, Wi02, Wi03, Wi04, Wi06, Wi07, Wi08, Wi22)
• CDS 131 - Linear Systems Theory (Fa18, Fa19, Fa20)
• CDS 140 - Differential Equations and Dynamical Systems (Wi11, Wi13, Wi14, Wi15)
• CDS 240 - Nonlinear Dynamical Systems (Sp14, Sp16)
• CDS 202 - Geometry of Nonlinear Systems (Wi93, Wi94, Wi04, Wi09, Sp13)
• CS 142 - Distributed Computing (Fa17, Fa19)
• CS 143 - Communication Networks (Fa18)
• Older courses (not taught in the last 15 years)
• Guest lectures - some individual lectures I have given in various courses

Contact

Mailing Address Richard M. Murray Control and Dynamical Systems 107-81 California Institute of Technology 1200 E. California Blvd Pasadena, CA 91125 USA	Contact information E-mail: murray@cds.caltech.edu Office: 109 Steele Lab, (626) 395-6460 Asst: Monica Nolasco, x4140 Labs: B112 Steele, 136 Keck
Other links Caltech Engineering and Applied Science Computing and Mathematical Sciences	Bioengineering Control and Dynamical Systems LinkedIn