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- 18:58, 10 December 2018 Jmarken uploaded File:Message Routing Schematic.png (Fig. 1: (a) A 3-node linear signal path built with two guide RNAs and one integrase. The signal plasmid originally starts in Cell A, and cannot be sent to Cell C as the address contains the C gRNA binding site. However, once the signal plasmid enters C...)