Networked Feedback Systems in Biology

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This is a joint project with John Doyle, funded by the ARO Institute for Collaborative Biotechnology. This page primarily describes the work done in Richard Murray's group.

Current participants:


We are developing a theoretical foundation for a network science relevant to the understanding and design of complex "systems of systems" typified both by biological networks and by the Army's Future Combat Systems (FCS). We are particularly focusing on the organizational principles underlying their ``robust yet fragile aspects, scalability, and evolvability, and demonstrating progress with case studies of varying detail using familiar and concrete examples from biological networks and network-centric technologies. Biological examples will focus on intracellular regulatory networks, intercellular communication, primarily in microbes and particularly with relevance to pathogenesis.