Fundamental Biological Factors Underlying Human Performance: From Molecular Diagnostics and Detection to Behavior and Systems Biology: Difference between revisions
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In collaboration with researchers at MIT (Lauffenburger) and ERDC (Perkins, Vinas) we are using zebrafish as a model organism for studying gut microbiome-brain interactions, with a focus on how the chemistry of the gut microbiome affects organism behavior, including sleep patterns and stress. Zebrafish provide an outstanding platform due to their maturity as a model organism as well as their transparent state as an embryo, allowing imaging of gut microbes and other biological features. | |||
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=== Objectives === | === Objectives === | ||
[[Image: | [[Image:arl19-zebrafish.png|right|400px]] | ||
Caltech's portion of the project focuses on two primary tasks: | |||
# The influence of gut microbiome on brain function: Diagnostics and logging of microbiotic environments in organisms | |||
# The influence of gut microbiome/brain interactions on the systems biology of performance | |||
=== References === | === References === | ||
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|Start date=1 Jan 2019 | |Start date=1 Jan 2019 | ||
|End date=30 Dec 2021 | |End date=30 Dec 2021 | ||
|Support summary=1 postdoc, 2 graduate students, research technician | |||
|Project ID=ARL19 zebrafish | |||
}} | }} |
Revision as of 23:02, 25 December 2018
In collaboration with researchers at MIT (Lauffenburger) and ERDC (Perkins, Vinas) we are using zebrafish as a model organism for studying gut microbiome-brain interactions, with a focus on how the chemistry of the gut microbiome affects organism behavior, including sleep patterns and stress. Zebrafish provide an outstanding platform due to their maturity as a model organism as well as their transparent state as an embryo, allowing imaging of gut microbes and other biological features.
Current participants: Additional participants: |
Collaborators: Past participants:
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Objectives
Caltech's portion of the project focuses on two primary tasks:
- The influence of gut microbiome on brain function: Diagnostics and logging of microbiotic environments in organisms
- The influence of gut microbiome/brain interactions on the systems biology of performance
References
- Analysis of Circuits for Dosage Control in Microbial Populations. Sophie J. Walton, Samuel E. Clamons, Richard M. Murray. Senior thesis.
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