Henrike Niederholtmeyer, Jan 2017: Difference between revisions
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23 Jan (Mon) | ==== 23 Jan (Mon) ==== | ||
* Arrive sometime before noon | * Arrive sometime before noon | ||
* 12 pm: Michaelle Mayalu seminar, 121 Annenberg (lunch) | * 12 pm: Michaelle Mayalu seminar, 121 Annenberg (lunch) | ||
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24 Jan (Tue) | ==== 24 Jan (Tue) ==== | ||
* Morning: work with Mark and Reed | * Morning: work with Mark and Reed | ||
* 12 pm: Seminar in 121 Annenberg (abstract below) | * 12 pm: Seminar in 121 Annenberg (abstract below) | ||
Revision as of 03:12, 12 January 2017
Henrike Niederholtmeyer will visit Caltech on 23-24 January 2017 to help us out with some microfluidics work we are doing. If you would like to meet with her, please sign up below.
Schedule
23 Jan (Mon)
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24 Jan (Tue)
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Seminar info
Gene expression in a synthetic tissue of artificial cells'
Henrike Niederholtmeyer and Neal K. Devaraj
Department of Chemistry and Biochemistry, University of California, San Diego, USA
Living cells in tissues or biofilms communicate with neighboring cells through chemical and mechanical signals allowing them to organize spatially. To reduce the complexity of these natural systems we create synthetic tissues of non-living artificial cells. We use a microfluidic method to produce porous capsules with an artificial “nucleus” where DNA is immobilized. Upon addition of transcription and translation reagents capsules synthesize proteins, which localize to nuclei containing binding sites. Neighboring capsules communicate by producing transcription factors that diffuse through the artificial tissue suggesting that it can serve as a model system to study pattern formation.
