Controlling biological networks by time-delayed signals

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G Orosz, J Moehlis, Richard M Murray
Philosophical Transactions of the Royal Society - A, 2009 (Submitted)

This paper describes the use of time-delayed feedback to regulate the behavior of biological networks. The general ideas are demonstrated on specific transcriptional regulatory and neural networks. It is shown that robust yet tunable controllers can be constructed that provide the biological systems with model-engineered inputs. The results indicate that time delay modulation may serve as an efficient bio-compatible control tool.