2009 ASCC workshop on biomolecular feedback systems

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9:00a   Workshop goals and introduction
9:15a   Review of basic concepts in biology
  • Central dogma
  • Simple ODE models for biological processes
10:15a   Break
10:30a   Analysis techniques
  • Use simple examples
  • Repression effects on noise, response time
  • Savageaumoics (repression versus activation)
11:30a   Examples from biology
  • More complicated system(s), with as much as can be analyzed
  • Eg, Chemotaxis, necessity of integral feedback
12:30p   Lunch
1:30p   Overview of biological circuit design
  • Synthetic biology
  • Molecular programming
2:15p   Robustness to uncertainty
  • Simple examples, without too much implementation detail
3:00p   Design of dynamics
3:30p   break
3:45p   Modularity
4:30p   Implementation
  • What can you actually do (limits of biomodularity, things that are easy to tune, etc)
  • Examples of devices: switches, oscillators (with "experimental" details) - how to build things
  • What can you measure (single cell microscopy, bulk measurements), inputs (IPTG, aTC, etc)
  • iGEM presentation?
5:15p   Future challenges (discussion)
6:00p   Adjourn