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	<title>Modeling Environmental Disturbances with the Chemical Master Equation - Revision history</title>
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	<updated>2026-04-15T07:17:07Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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		<id>https://murray.cds.caltech.edu/index.php?title=Modeling_Environmental_Disturbances_with_the_Chemical_Master_Equation&amp;diff=19711&amp;oldid=prev</id>
		<title>Murray: htdb2wiki: creating page for 2013b_ybm13-cdc.html</title>
		<link rel="alternate" type="text/html" href="https://murray.cds.caltech.edu/index.php?title=Modeling_Environmental_Disturbances_with_the_Chemical_Master_Equation&amp;diff=19711&amp;oldid=prev"/>
		<updated>2016-05-15T06:15:24Z</updated>

		<summary type="html">&lt;p&gt;htdb2wiki: creating page for 2013b_ybm13-cdc.html&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{HTDB paper&lt;br /&gt;
| authors = Enoch Yeung, James L. Beck, and Richard M. Murray&lt;br /&gt;
| title = Modeling Environmental Disturbances with the Chemical Master Equation&lt;br /&gt;
| source = Submitted, 2013 Conference on Decision and Control (CDC)&lt;br /&gt;
| year = 2013&lt;br /&gt;
| type = Conference Paper&lt;br /&gt;
| funding = &lt;br /&gt;
| url = http://www.cds.caltech.edu/~murray/preprints/ybm13-cdc_s.pdf&lt;br /&gt;
| abstract = &lt;br /&gt;
In this paper we consider the problem of repre- senting a biological system and its environment using a stochas- tic modeling framework. We first introduce a decomposition of the global chemical reaction system into two systems: a system of interest and its environment. We then present and derive a decomposition of the chemical master equation to achieve a representation describing the dynamics of the system of inter- est, perturbed by an environmental disturbance. We use this decomposition to model examples of two types of environmental disturbances: the disturbance a system experiences through loading effects from limited resources and the disturbance a system experiences when perturbed by an antibiotic that modifies transcription or translation rates.&lt;br /&gt;
| flags = &lt;br /&gt;
| tag = ybm13-cdc&lt;br /&gt;
| id = 2013b&lt;br /&gt;
}}&lt;/div&gt;</summary>
		<author><name>Murray</name></author>
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